NCI-2021-10597

A Phase 1 Open-Label, Dose-Escalation and Cohort Expansion Study of LUNA18 Monotherapy and Combination Therapy in Patients with Locally Advanced or Metastatic Solid Tumors

This is a Phase 1 study testing a drug called LUNA18 in patients with locally advanced or metastatic solid tumors (cancers that are hard to treat or have spread to other parts of the body). The study will look at how LUNA18 works on its own (called monotherapy) and also when combined with other treatments. The researchers will start with small doses and gradually increase them to find the best dose that works. The study is focused on checking how safe the drug is, how the body processes it, and how well it can treat these types of cancer.

Phase 1: First step in testing a new medicine in people, and tests if treatment is safe, determines the right dose, and checks for any side effects.

For more information about the trial, click the link below:

https://clinicaltrials.gov/ct2/show/NCT05012618

Clinical Trial Site: Sinai

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