NCT-04410796

A phase 2 randomized study of osimertinib versus osimertinib plus chemotherapy for patients with metastatic EGFR-mutant lung cancers that have detectable EGFR mutant cfDNA in plasma after initiation of osimertinib treatment

It's a Phase 2 trial comparing osimertinib alone to osimertinib with chemotherapy for people with advanced lung cancer that has a certain genetic change with an EGFR mutation. They're looking specifically at those whose blood shows an EGFR mutation. 

EGFR: Epidermal Growth Factor Receptor (EGFR) is on the surface of cells and helps them grow and divide. In cancer, EGFR is like a switch that gets stuck in the "on" position, making cells grow and divide too much.

mutation: Mutation is an alteration in the genetic material of a cell or a virus that can be inherited by its descendants

For more information about the trial, click the link below:

https://clinicaltrials.gov/ct2/show/NCT04410796

Clinical Trial Site: Columbia

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